Več informacij ― Slovenščina

Pigmented purpuric dermatoses (PPD) je skupina kožnih stanj, ki jih zaznamujejo majhna področja krvavitve pod kožo zaradi vnetja kapilar. PPD se običajno začne kot rdeče do vijolične lise, ki kasneje postanejo zlato-rjave, ko se hemosiderin ponovno absorbira.
Pigmented purpuric dermatoses (PPD) include several skin diseases characterized by multiple petechial hemorrhage as consequence of capillaritis. PPD generally present with red to purple macules that progressively evolve to golden-brown color as the hemosiderin is reabsorbed.

Schamberg disease je najpogostejša vrsta pigmented purpuric dermatoses (PPDs) , ki so kronične kožne bolezni, za katere so značilne majhne rdeče ali vijolične lise in povečana obarvanost kože (rjave, rdeče ali rumene lise) . PPD so razvrščeni v pet vrst: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura, and eczematoid-like purpura of Doucas and Kapetanakis. Schamberg disease (SD) je znan tudi kot progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressiva, and Schamberg's purpura. Prizadene predvsem moške in se običajno pojavi na spodnjih nogah, lahko pa tudi na stegnih, zadnjici, trupu ali rokah.
Schamberg disease represents the most common type of pigmented purpuric dermatoses (PPDs), a chronic, benign, cutaneous eruptions characterized by petechiae, purpura, and increased skin pigmentation (brown, red, or yellow patchy). The PPDs are grouped into five clinical entities: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura and, eczematoid-like purpura of Doucas and Kapetanakis. Schamber disease (SD) has also been called: progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressive and, Schamberg's purpura. It is commonly seen in males and mainly affects the tibial regions, and could involve thighs, buttocks, trunk, or upper extremities.

Analizirali smo podatke o 113 bolnikih s PPD, vključno z 38, ki so bili podvrženi biopsiji kože za to študijo. Najpogostejši klinični tip je bila Schambergova bolezen (60,5 %) . Druga stanja poleg PPD so bila hipertenzija (15,8 %) , sladkorna bolezen (10,5 %) in drugi. Zgodovina zdravil je razkrila statine (13,2 %) , zaviralce beta (10,5 %) in druge. Možni dejavniki, povezani s PPD, so vključevali nedavno okužbo zgornjih dihal (5,3 %) , dolgotrajno stanje, ki je povzročilo visok ortostatski tlak (2,6 %) , in naporno vadbo (2,6 %) . Zdravljenje je prejelo 36 bolnikov (94,7 %) - oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.
Information on 113 patients with PPD was analyzed, and 38 subjects with skin biopsy were included for this study. Schamberg's disease was the most frequent clinical type (60.5%). Concomitant diseases included hypertension (15.8%), diabetes (10.5%), and others. Associated medication histories included statins (13.2%), beta blockers (10.5%), and others. Possibly associated etiologic factors were recent upper respiratory infection (5.3%), high orthostatic pressure due to prolonged standing (2.6%), and strenuous exercise (2.6%). A total of 36 patients (94.7%) were treated with one or more treatment methods, including oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.